Androgen receptor in serially subcultured human endometrial fibroblasts.
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چکیده
منابع مشابه
Androgen receptor in serially subcultured human endometrial fibroblasts.
Specific dihydrotestosterone (DHT) binding was demonstrated in the whole cell sonicates obtained from serially subcultured human endometrial fibroblasts. This binding showed a high affinity and specificity for DHT (Kd=3.3 X 10(-10) M). Various kinds of excess nonradioactive steroids were arranged, as a result of competition among them, in the following decreasing order of binding affinity: DHT,...
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The androgen receptor (AR) is known to play critical roles in the malignancy of prostate cancer as well as the management of male reproductive organs. Endometrial carcinoma, one of the major female cancers, is considered an androgen-related cancer. However, the importance of androgen signaling through its receptor in endometrial carcinomas has not yet been clarified. We recently demonstrated th...
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ژورنال
عنوان ژورنال: Endocrinologia Japonica
سال: 1980
ISSN: 0013-7219,2185-6370
DOI: 10.1507/endocrj1954.27.477